Dr. Shaun Fleming
Clinical and Laboratory Haematoligist
Lead in Acute Lymphoblastic Leukaemia – Alfred Health
Co-chair of the optimal care pathway project in Acute Lymphoblastic Leukaemia, Australia
Adolescent and Young Adult patients represent a unique group in the management of Acute Lymphoblastic Leukaemia, where with the use of paediatric inspired regimens incorporating the use of asparaginase superior outcomes can be attained as compared to when adult regimens are utilised, though their outcome remains inferior to that of children.
AYA patients bring unique aspects to the management of asparaginase with a divergent toxicity profile from that seen in paediatric patients. We will discuss these aspect to management and the Australian experience with the use of paediatric inspired regimens in AYA patients.